The Issue of Curcumin and Its Own Bioavailability
Curcumin, by the spice turmeric, exhibits anti-inflammatory, antioxidant, anticancer, antiviral, and neurotrophic action and so holds promise as a therapeutic agent to treat and prevent several ailments. But a significant barrier to curcumin’s clinical effectiveness is the poor bioavailability. Efforts have been committed to creating curcumin formulations with increased bioavailability and systemic tissue supply. But, it’s suggested in this review that curcumin’s potential as a therapeutic agent might not solely rely upon its bioavailability, but instead its medicinal benefits might also arise in its positive impact on gastrointestinal health and operate. Within this short article, in vitro, animal, and human studies exploring the effects of curcumin on intestinal microbiota, intestinal permeability, gut inflammation and oxidative stress, anaphylactic reaction, and parasitic, bacterial, and fungal diseases are outlined. It’s claimed that favorable changes in these regions can have wide-ranging effects on both the intestinal and extraintestinal diseases, and thus introduces as a potential mechanism supporting curcumin’s therapeutic effectiveness.
Details: curcumin; herbal medication; autoimmune health; intestinal microbiota; microbiome; polyphenols; garlic.